20240101 Censorship of Gay art, Vaccine development, lots of time devoted to fighting in Dallas. HIV cure research.
The fighting in Dallas took a huge amount of time last week, but I hope to start showcasing Gay artists again.
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Another artist wiped out by Facebook
I saw a complaint on Facebook by a Gay artist that Facebook had blocked his ability to post on his personal page. I looked at it, just life drawings of nudes that you would find in an art class. Then Sunday, I saw it was completely wiped out of content.
https://www.facebook.com/john.revelator.94
The person doesn’t have screen captures of any notices.
I strongly recommend every Gay artist get on X (formerly Twitter) and create a Substack newsletter for their art.
I did discuss organizing in this post, but no one messaged me.
This repression isn’t being done by the Christian right, it is being done by corporate America and there doesn’t seem to be any concern by the LGBTQXYZ leadership.
I want to start show cases Gay artists again.
I do all the work, you merely have to give me permission to use your artwork. Loot at these showcases to see how I do it.
Some of this Youtube channel’s productions I think might be of interest to Gays.
He has put a lot of effort into it.
A Fairly good depiction of what happens when you get an erection and cum.
The 2010 Bathhouse raid in Dallas, Texas
I wrote up a history with all the available resources and I have Freedom of Information Act request to get the police raid information from the Cityof Dallas.
This took a huge amount of time, and away from the Gay Partisan newsletter.
This raid made the list of the top 30 raids of world historical importance.
https://www.advocate.com/politics/2018/2/02/30-infamous-police-raids-gay-bars-and-bathhouses
Did a mass mailing to the executives and board of directors of Nextdoor and the members of the San Francisco human rights commission and their LGBT advisory board.
We had a post on Nextdoor removed after it being attacked by the Nextdoor Review Team member who uses the term sodomite.
It was 47 envelops with materials. I think the bullying of Gays on Nextdoor and Reddit needs to stop. I don’t have the effort online at the local Dallas Gay Liberation newsletter. I don’t want to give the local homophobes any advanced notice.
I figure if Gays in the Dallas area are getting bullied, probably it is happening elsewhere. I will post a link when I have it online. It will likely start arriving there late this week or early next week.
I think the use of the term “sodomite” is what is going to embarass Nextdoor and get them to act.
What I am looking for is some connection to activist there. Facebook, Reddit, and Nextdoor have their headquarters there.
With the two Dallas projects, I was exhausted by Sunday.
Progress on getting a syphilis vaccine isn’t good
You would think with the importance of this to the health of Gay men it would be an important agenda item and also mentioned in LGBT publications. However, there isn’t much G in the LgBT anymore.
This really needs to get on the political agenda. It is a matter of funding.
https://pubmed.ncbi.nlm.nih.gov/37090699/
This report of improvements for HIV vaccines has weak suggestions. (NOT mRNA vaccines.)
This is about enhancing the technology that has been used for HIV vaccines using the existing pre-mRNA vaccine technologies.
The article is hoping for some incremental improvements to get the vaccine over the finish line. It might work, and there might be an HIV vaccine with some effectiveness, but enhancing a failing method isn’t very promising.
They should try. The mRNA vaccine might not work, or it will need to be done with the other type of non-mRNA vaccines to be effective.
Also, as they have vaccines that fail, they do learn about HiV and the immune system. So I support these efforts, but I am not hopeful
The mRNA HIV vaccine is at Phase 1.
https://www.modernatx.com/en-US/research/product-pipeline
The vaccine was announced a big success. Perhaps they are in the progress of designing the Phase 2 and organizing and planning it. I couldn’t find anything on their website.
Currently this is the only vaccine candidate that seems hopeful.
One of the things is that it seems mRNA vaccines and therapeutics have many, many applications. Even when they get these 40+ projects done, they very easily could do another 40. With circular mRNA technology being developed and self-amplying mRNA technology being developed, there is probably not enough researchers to chanse all the opportunitie.
The good news is that HIV and the herpes viruses are a priority for Moderna as well as Hepititis C, so the medical needs of the Gay community are being met.
N-803 New approach to HIV cure.
Even with the HIV vaccine being released, we will want to have cures. Besides the issue of curing a huge number of Gay people, we can’t expect a vaccine to be 100% effective.
N-803. This is an approach to go after HIV virus hiding out in the lymph nodes and elsewhere.
The title of this first report is:
“Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial.”
This is the Phase I trial, which is to make sure it doesn’t kill you, injure you or make you really, really sick. It is a typical Phase I trial report. Very technical. You can skip reading it, their conclusion is that the medicine can be taken up to a certain dose leve.
https://pubmed.ncbi.nlm.nih.gov/35102335/
A phase 1 needs to be done before they can go to phase 2, which is preliminary testing for effectiveness.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537516/
This is the abstract for the above article.
In spite of the advances in antiretroviral therapy to treat HIV infection, the presence of a latent reservoir of HIV-infected cells represents the largest barrier towards finding a cure. Among the different strategies being pursued to eliminate or reduce this latent reservoir, the γc-cytokine IL-15 or its superagonist N-803 are currently under clinical investigation, either alone or with other interventions. They have been shown to reactivate latent HIV and enhance immune effector function, both of which are potentially required for effective reduction of latent reservoirs. In here, we present a comprehensive literature review of the different in vitro, ex vivo, and in vivo studies conducted to date that are aimed at targeting HIV reservoirs using IL-15 and N-803.
The article says there are two clinical studies at the recruiting phase to start doing Phase 2 studies to basically see if the therapy works. Phase 3 is when you test a large group of people.
According to this webpage, they are in Phase 3 and the research is being done in Thailand. They expect that the Phase 3 will be completed Nov. 30, 2027. It is going to take a while. Basically you have to give them the medicine and wait some time to get results.
https://www.rihes.cmu.ac.th/news/14321?lang=en
N-803 is being used in a lot of cancer research, so you need to filter to get specific HIV results.
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I hope things will get better next year.