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VACCINE PROTECTION AGAINST GONORRHEA
(1/13/2023)
PRECLINICAL GONORRHEA VACCINE TEST RESULTS
This is NOT an mRNA vaccine, but uses another method. Biomolecular science is developing and as a result many possibilities for vaccines are opening up.
The favorable test results are with animal models.
Earlier this newsletter had a post with a report on how a meningitis vaccine was found to provide partial protection against gonorrhea.
(11/21/2022)
MENINGITIS VACCINE MAY OFFER PROTECTION AGAINST GONORRHEA
It appears that the vaccine for meningitis offers some protection against gonorrhea.
The meningitis vaccine is something you can get right now to protect yourself against meningitis and something Gays should get anyways. There have been incidents of Gays dying of meningitis. (Links to reports of meningitis deaths later in article.)
This is the link to a report some studies at the Univ. of Minnesota.
It appears only about 40% effective, but that is better than no protection and it is a benefit from a vaccine you should be getting anyways. The following is an article of an outbreak of meningitis among Gay men
Because it is Florida they can’t get effective information about deaths, but there have been deaths as reported below.
https://www.cnn.com/2022/06/22/health/florida-meningococcal-disease-outbreak/index.html
https://www.cbsnews.com/news/meningococcal-disease-outbreak-florida-7-deaths-cdc/
You should get vaccinated against meningitis any ways and as a bonus there is partial protection against gonorrhea.
Remember that a Gay anti-vaxxer has a higher chance of giving you gonorrhea.
This is the heavy duty scientific article about working with a meningitis vaccine to have it work on gonorrhea.
https://www.nature.com/articles/s41541-021-00388-3
RESEARCH INTO GONORRHEA VACCINES
There is a developing technology on a possible vaccine for gonorrhea by a company called LimmaTech using vaccine technology developed at the Univ. of Queensland in Australia.
https://lmtbio.com/gonorrhoea-std-platform/
The above webpage shows that before the year 2030 there is likely to be an untreatable form of gonorrhea. You would think that vaccine development for gonorrhea would be an urgent priority but with so many letters in LGBTQIAPP… the needs of the G get lost in the shuffle. Plus, Stonewall Democrats and other Respectability Gays are too embarrassed by the issue of Gays getting gonorrhea to address this urgent health need.
One of the issues of not having Gay centric groups is that issues vital to the Gay community aren’t a focus or sometimes not even addressed.
Older Material
This isn’t even a news item with the LGBTQXYZ press. I suppose the Respectability Gays would be embarrassed. Also the LGBTQXYZ and the Stonewall Democrats don’t really have much “G” in their agenda.
This is a plan to reduce the incidence of gonorrhea in the Gay community and how it would be effective with even a vaccine with low protection and short duration.
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00760-X/fulltext
Is any organization in the “queer” community pushing this?
Also, it seems that the vaccine against meningitidis somewhat works against gonorrhea.
https://arstechnica.com/science/2022/04/incurable-gonorrhea-there-may-already-be-a-vaccine-for-that/
The Alphabet Democrats simply aren’t driving an agenda for Gay health that allows for sexual liberation. I provide a link at the end of this article.
Syphilis Vaccines
(11/14/2022)
VACCINE DEVELOPMENT FOR SYPHILIS
Gays would one of the major beneficiaries if there was a vaccine for syphilis. It is true that there are antibiotics to treat syphilis, but there is also the issue of antibiotic resistance.
https://www.frontiersin.org/articles/10.3389/fimmu.2022.952284
Anti-Gay forces have used the issue of the incidence of syphilis and other diseases among Gays as a justification for anti-Gay sex laws in arguments that homosexual acts should be illegal as a public health measure.
Yet, it isn’t even an issue in the LGBTQXYZ press and certainly not an agenda item for the Stonewall Democrats and other LGBTQXYZ type organizations. They would be too embarrassed to make it a part of their agenda. All the Gays are supposed to be getting married and be monogamous, and in their minds, only the bad Gays need a vaccination for syphilis.
Herpes Vaccines
(1/13/2023)
BIONTECH HERPES mRNA VACCINE TRIAL STARTS
They are also working on malaria and tuberculosis. I speculate that they can only work on so many vaccine development projects at the same time, but as one vaccine triumphally rolls out, they will move on to the next.
Since these vaccine trials are moving way faster than traditional vaccine developments, I think that we can expect that ALL the major STDs that impact Gays will have either have vaccines or vaccines in development in maybe 5 years. I think some of the major STDs that Gays face will have mRNA vaccines sooner.
(12/26/2022)
VACCINE NEWS FOR HERPES
https://www.nature.com/articles/d41586-022-04444-3
Only the first section is about vaccines, and mentions two separate efforts to have mRNA vaccines for genital herpes.
One important thing to notice is that there are multiple diseases for which they are working on mRNA vaccines. Likely they can’t work on every disease at once for which a mRNA vaccine might work, so if a disease isn’t being worked on now, it likely will be on the list for the next thing they work on. This is only my thought; I don’t have a source for it.
General Vaccine Research News
(10/11/2022) RESEARCH INSTITUTION OPENING UP FOR HIV VACCINE.
This grant and the launching of a multi-institute effort reflects the growing optimism about finding both a vaccine and cures for HIV.
I follow the articles on molecular biology in the scientific press, but I think the average person isn’t really aware that the biotechnology has really sped up in how fast it advances and how much the understanding and the technology for molecular biology is advancing.
There are new things like mRNA vaccines, but there are other developments in scientific instruments, molecular biology, biotechnology which suddenly make a lot of things possible that weren’t possible before.
For example, it use to take years to figure out the structure of a protein and it involved tedious work of trying to crystalize them and then x-ray diffraction and powerful computers to work on the diffraction problems. Some proteins just wouldn’t crystalize. They even did experiments crystalizing a protein in space to get a structure. Mathematicians, programmers and molecular biologists were working on the problem for decades with little success. They even had a conference about how they were totally failing to figure out what to do.
A lot the development of medicines for diseases and ailments depends on knowing the structure of proteins. Here a piece of software works out the structures of 660 million of them.
https://www.nature.com/articles/d41586-022-03539-1
What is the point of discussing protein folding? To show that molecular biology is moving really fast. The situation where progress was slow and achieved with really determined work is moving to a situation where things are moving much faster and solutions to problems come with lots less work.
mRNA HIV VACCINES
(3/20/2023)
Update status of HIV mRNA status.
This has some timeline information which earlier articles didn’t have. Also, it is a good overview article which is written for the general reader.
https://covid19.nih.gov/news-and-stories/mrna-vaccine-technology-promising-idea-fighting-hiv
(8/16/2022)
OPTIMISTIC THAT HIV mRNA VACCINE MIGHT BE COMING SOON AND WHY.
It also explains why mRNA vaccines can overcome problems that other vaccines have in protecting people from HIV.
(3/23/2022)
HIV mRNA VACCINE EFFORT ARTICLE – TITLE TOO PESSIMISTIC BUT IT IS INFORMATIVE.
The research does NOT say that it is a long way off. What the researcher said was:
“We don’t really know how far away or how close we are,” Himansu added. “We’re trying to pursue many approaches in parallel, because we don’t know what’s going to work.”
Himansu also said:
In other words, what’s being tested now is not an HIV vaccine itself but the possible eventual components of one. An effective and approved vaccine sequence could still be 10 or 15 years away, Himansu said.
The word is “could.”
Dr. Himansu is correct in what he says. Until it is done you don’t know how long it is going to take, and as with cancer and other potentially fatal diseases is you don’t want to give false hope. With the long history of HIV vaccine failures that used the usual methods of making vaccines that is also the correct response for this reason. Popular reporting on medical research often gives a lot of false hope as if the research might mean a medical breakthrough is imminent. When my mother had breast cancer she would call once a week about some development and I as a subscriber to Science magazine, which also reported on the development, I had the disagreeable task of explaining what the significance of the research was, which wasn’t an imminent, which is what she needed to save her life. Medical researchers are very aware of this type of news reporting.
However, two notable things about mRNA vaccines are how fast they can be developed and with the COVID-19 vaccine, how extremely effective both Moderna and Pfizer are, both in the 90% range. Further mRNA technology can design vaccines to do things that the other vaccine technologies can’t do and very specifically. They call mRNA vaccines the first “digital vaccines.”
Also, as the article does explain though how the HIV mRNA vaccine effort has means of progressing must faster than other vaccine efforts and is correct in this.
Perhaps the author of the article wanted to make sure people didn’t think the vaccine was going to be available Fall 2022. Given how fast the Coronavirus vaccine became available, 3 or 4 months, they might.
This item will be added into the HIV Vaccine Page. Link at the end of the newsletter.
MORE ARTICLES FOLLOW BELOW.
https://www.poz.com/article/new-study-evaluating-three-mrna-hiv-vaccine-candidates
https://www.nih.gov/news-events/news-releases/nih-launches-clinical-trial-three-mrna-hiv-vaccines
HIV vaccines using other technologies.
(11/0/2023)
New HIV vaccine trail has been started. Uses CMV virus vector, not mRNA.
We don’t have all the eggs in one basket. And if this vaccine works and the mRNA works, likely getting both vaccines will give an even better immunity.
Another article about it.
https://jamanetwork.com/journals/jama/fullarticle/2810575
(2/27/2023)
NEW VACCINE TECHNOLOGY THAT COULD BE USED FOR HIV
All of biotechnology and medical science is moving forward now faster than ever before.
(1/18/2023)
THIS FAILED HIV VACCINE IS NOT A mRNA Vaccine
(12/2/2022)
ENCOURAGING INITIAL RESULTS FOR SCRIPPS INSTITUTE VACCINE - NOT AN mRNA VACCINE.
This is the much more technical article in Science to which they refer.
https://www.science.org/doi/10.1126/science.add6502
HIV Cure News
(11/4/2022)
PROGRESS ON THERAPY FOR THOSE ALREADY INFECTED.
This is work towards a cure rather than prevention.
If you read it, it is 40% were able to stay off the HIV medicine for six-months. That is two out of five and may not seem all that great. Science doesn’t work like in the movies where there is a eureka moment and everything is solved.
It is testing the first attempt, see if it works at all, then go back and do more work to make it better on the second attempt. Sometimes you have to do it and see if it works at all to see if it is worth working on, and then to find out what the other issues are.
https://www.aelixtherapeutics.com/
The idea that a HIV vaccine could be used to cure HIV is something entirely new.
This article also shows that the possibly ways to go after HIV and prevent it or cure it are increasing.
(8/00/2022)
mRNA wakes up HIV virus providing possibly an avenue to attack the virus.
They are intended to provide immunity to Covid, but a new thing has been discovered. They wake up HIV virus hiding out in cells.
During anti-viral therapy HIV hides out in cells waiting for the therapy to stop. Finding this hidden virus, “waking it up,” so the immune system would go after it, has been a goal of scientists working on HIV.
Turns out that mRNA HIV vaccines wake up the hiding virus so it can be found by the immune system. This is not a cure in itself, but an important and unexpected step in finding a cure. This is an initial result, and of course scientists will build on it.
This is an important article on this at Cornell Univ. (No content-farm sources in my newsletter)
This link following is the really technical article which probably only a scientist in that field would understand. HOWEVER, you can read the abstract (It is fairly challenging also). I also put it here to show that this result is accepted by leading scientific authorities.
https://www.nature.com/articles/s41467-022-32376-z
The important thing is that a new possible avenue to finding a cure for HIV has been found and of course scientists will work on making it better. There will be cycles of development, experimentation, and re-development.
At this point the Gay community is overwhelmingly NOT anti-vaxxer. We need to keep it that way to have a victory over HIV. I provide a meme at the very, very end of the newsletter that you might use against anti-vaxxers. If you see some meme that you think would work to fight anti-vaxxers at my newsletter, feel free to use it.
(3/18/2022)
A vaccine is of course going to be the first line of defense against HIV. However, a cure will still be needed. There will be breakthrough infections that happen. Though in the United States herd immunity might happen, with the proliferation of anti-vaccine lunatics, there will unfortunately be sources of HIV among straight people and stupid Gays who follow anti-vaxxer ideology. Overseas there will be populations that have a low level of vaccinations. The efforts to erradicate polio through the use of vaccines keeps being almost, but just short of success since there will be some war zone where people can’t be vaccinated and polio exists, or some local resistance to vaccination.
So a cure is necessary. Progress is being made on an HIV cure. Biomolecular science and immunology have been advancing immensely in the last few decades. For those who aren’t readers of the scientific press it probably isn’t apparent, but there are things they can do now that were only dreams a decade or two ago.
It needs to be understood that even if one of these technologies by itself doesn’t cure HIV, it might be part of a combination therapy. Or it might be of use in some specialized cases. Even failures will result in some new knowledge about HIV.
HIV empowers the agendas of respectability Gays. It puts a damper on sexual liberation. It also helps create a phalanx of social workers who will tend to push social worker attitudes on the Gay community. A vaccine and cure will disempower them considerably.
This is a companion page to the HIV vacine Page, I will put a link at the bottom of the page. There is a HIV general news page also the link to which is at the bottom of this page.
ARTICLES
For this page I am going to have some links with explanations grouped together. They will be in order of newest to oldest.
CRISPR TECHNOLOGY TO CUT HIV PROVIRUS OUT OF THE CELLS
A provirus is a virus which has been inserted into a cell’s genetic material where it then acts to create more virus particles. HIV hides out in the patients genetic material when it is suppressed with anti-virals. It is also the place where the disease works to create other viral particles to infect other cells. So a technology that could pull out HIV from a cell and render it harmless would be potentially a cure for HIV infection.
These researchers are targeting a cure with one treatment, but my uninformed opinion is that if they can do it with three treatments that is still a great accomplishments. Also, if they can just reduce the hidden virus 90%, it probably has some benefit, though I am not sure what.
CRISPR is a gene editing tool where you can cut at a specific location in DNA, cut out a specific segment, and insert genetic code into the DNA. CRISPR didn’t exist until recently, like the last five years roughly.
There are a lot of new biological technologies that didn’t even exist before 2010 and there are a lot of new ones since then. Doctors and scientists are looking at their application to HIV. There are two companies pursuing the use of this technology at the present. Possibly there are more efforts underway.
The following is in reference to a company called Excision:
These following studies are about a clinical trial using CRISPR to cut out HIV from infected cells. They are talking about a one-time treatment for HIV.
Update (10/6/2022) https://arstechnica.com/science/2022/10/a-bold-effort-to-cure-hiv-using-crispr/
https://www.phillyvoice.com/hiv-cure-research-temple-clinical-trial-crispr-gene-editing-/
There are multiple new technologies out there and we should expect that new approaches for treating HIV are going to be pursued.
The effort isn’t at just one university either which is good. A potential CRISPR cure isn’t dependent on just one team. Though the different groups in publishing are sharing their results.
The following are about the efforts of Exavir:
This is a paper, highly technical of HIV CRISPR research at the Univ. of Nebraska.
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00472-2/fulltext
This is about the company they founded.
https://www.unmc.edu/pharmacology/products-services/NNPP/collaboratories/Exavir_Therapeutics.html
GROUP - FLUSHING HIV OUT OF ITS HIDDING PLACE.
The following article is somewhat technical and you only can see the abstract.
https://www.science.org/doi/10.1126/scitranslmed.abl3836
This is a popular article.
Basically what happens with AIDS patients getting anti-virals drugs is that the HIV virus hides out in certain cells and says quiet (inactive) so there aren’t foreign proteins for the immune system to find, detect and get rid of the infected cells.
This isn’t a cure in itself, but it is significant progress towards getting a cure.
Other HIV Articles
New technology and method to investigate HIV infection.
The importance of this article is to realize that new technologies to investigate HIV and viral infection in general are being developed all the time.
Links to other aspects of vaccination.